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130 Comparatively, the deficiency of ZIP8 has a substantial impact on zinc influx in effector T cells and results in reduced TCR-mediated signaling, including NF-B and MAPK signaling, which are involved in the differentiation of T helper (Th)17 cells

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In an article by the NCBI on the role of carnitine in disease, the NCBI stated that: Nutritional supplementation of L-carnitine can enhance nerve conduction and reduce neuropathic pain in diabetic patients and can save the lives of patients with primary carnitine deficiency